The interaction with the drug will result in the protease being A - VCE - SSCE Biology - Question 11 - 2023 - Paper 1

In examining the interaction between a drug and a protease, we need to consider how the drug influences the stability and activity of the enzyme. The four options provided represent different biochemical reactions that could occur.

• Denatured: This suggests that the drug would alter the structure of the protease, leading to loss of its functionality.
• Activated: This would imply that the drug enhances the protease's activity, which is less common in drug interactions designed to inhibit proteases.
• Catalysed: This option indicates that the protease aids in facilitating a reaction, which typically does not describe the impact of drugs directly.
• Inhibited: This is likely the most relevant choice, as many drugs are designed to inhibit the activity of enzymes, including proteases, thus blocking their function.

In this case, based on common pharmacological effects, the best answer is D. inhibited.