Liposomes are found in the cytosol and are formed from a double layer of phospholipid molecules identical to those found in plasma membranes - VCE - SSCE Biology - Question 2 - 2007 - Paper 1
Question 2
Liposomes are found in the cytosol and are formed from a double layer of phospholipid molecules identical to those found in plasma membranes. Liposomes can also be m... show full transcript
Worked Solution & Example Answer:Liposomes are found in the cytosol and are formed from a double layer of phospholipid molecules identical to those found in plasma membranes - VCE - SSCE Biology - Question 2 - 2007 - Paper 1
Step 1
A. drug 1 is lipophilic.
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Answer
Given the structure of liposomes, which have a hydrophilic exterior and a hydrophobic core, it is reasonable to conclude that drug 1, which is located in the hydrophobic region of the liposome, is lipophilic. Lipophilic substances tend to dissolve in lipid layers.
Step 2
B. drug 2 is water soluble.
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Answer
Drug 2 is shown in the diagram to be located in the outer aqueous environment of the liposome. This suggests that drug 2 is water soluble, allowing it to interact with the surrounding aqueous solution.
Step 3
C. the interior of the liposome is aqueous.
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The interior of the liposome is filled with an aqueous solution, which is typical for liposomes. This allows for the encapsulation of water-soluble drugs and provides a medium for them to be delivered into cells.
Step 4
D. liposome-based membranes have a rigid structure.
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Liposome membranes are made of phospholipid bilayers, which are flexible and not rigid. This flexibility is essential for the functionality of liposomes, allowing them to merge with cell membranes and deliver their contents effectively.
