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In animal cells, tight junctions are multi-protein complexes that mediate cell-to-cell adhesion and regulate transport through the extracellular matrix - VCE - SSCE Biology - Question 7 - 2016 - Paper 1

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In animal cells, tight junctions are multi-protein complexes that mediate cell-to-cell adhesion and regulate transport through the extracellular matrix. Proteins tha... show full transcript

Worked Solution & Example Answer:In animal cells, tight junctions are multi-protein complexes that mediate cell-to-cell adhesion and regulate transport through the extracellular matrix - VCE - SSCE Biology - Question 7 - 2016 - Paper 1

Step 1

nucleus – ribosome – endoplasmic reticulum – vesicle – Golgi apparatus.

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This sequence highlights the critical pathway proteins take for assembly. Initially, the gene for the protein is transcribed in the nucleus. Then, the ribosome translates the mRNA into a polypeptide chain in the endoplasmic reticulum (ER), where it begins to fold into its functional form. After being synthesized, the protein is packaged into a vesicle that transports it to the Golgi apparatus. At the Golgi, further modifications and sorting occur before the protein is dispatched to its final destination, which supports the function of tight junctions.

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