In 2009, a report stated that influenza viruses resistant to Relenza had been identified - VCE - SSCE Biology - Question 31 - 2019 - Paper 1
Question 31
In 2009, a report stated that influenza viruses resistant to Relenza had been identified. Resistance occurred because of a mutation in the viral DNA. This mutation c... show full transcript
Worked Solution & Example Answer:In 2009, a report stated that influenza viruses resistant to Relenza had been identified - VCE - SSCE Biology - Question 31 - 2019 - Paper 1
Step 1
A. the enzyme needed for ongoing virus replication.
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Answer
The mutation causing glutamine to replace lysine would likely affect the enzyme's structure. Enzymes are highly specific proteins, and even small changes in their amino acid sequence can alter their shape and charge, impacting their functionality and, in this case, reducing the effectiveness of Relenza.
Step 2
B. the ribosomes of the influenza virus.
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Ribosomes are vital for protein synthesis, but they are not directly involved in interactions with antiviral medications like Relenza. Changes in the viral genetic material do not generally alter ribosomal function.
Step 3
C. the capsule of the influenza virus.
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The capsule (or envelope) of a virus is primarily made of lipid membranes and proteins. While mutations can alter surface proteins, the question specifically emphasizes change related to Relenza interaction, which is more associated with viral enzymes.
Step 4
D. Relenza.
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Relenza is an antiviral drug that inhibits viral neuraminidase, so it cannot change itself due to mutations in the virus. Instead, mutations in the virus could affect how Relenza interacts with the viral components.
