Bevacizumab is a humanised monoclonal antibody that is used to treat several different cancers - VCE - SSCE Biology - Question 27 - 2023 - Paper 1

Humanising monoclonal antibodies like bevacizumab helps to minimize the body's immune response to the foreign components of mouse-derived antibodies. By incorporating human components into the antibody structure, the likelihood of the immune system recognizing it as a foreign substance decreases. This results in improved therapeutic efficacy and reduced side effects due to a lower rate of antibody neutralization by the immune system.