Cancer is a disease characterised by the rapid multiplication of cells - VCE - SSCE Biology - Question 8 - 2009 - Paper 1
Question 8
Cancer is a disease characterised by the rapid multiplication of cells. It is often treated with the use of chemicals, however damage may occur to non-cancer cells.
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Worked Solution & Example Answer:Cancer is a disease characterised by the rapid multiplication of cells - VCE - SSCE Biology - Question 8 - 2009 - Paper 1
Step 1
Explain how damaging bone marrow cells could be life threatening.
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Answer
Bone marrow is essential for producing blood cells, including red blood cells and white blood cells. Damage to bone marrow can lead to a shortage of these cells, which can cause severe health issues. For example:
Red Blood Cells: If red blood cell production is compromised, it can lead to anemia, resulting in fatigue and weakness due to insufficient oxygen supply to tissues.
White Blood Cells: A reduction in white blood cells can impair the immune system, making the body more susceptible to infections.
B Lymphocytes: Bone marrow also produces B cells, which are vital for antibody production. A lack of B cells can prevent the body from effectively responding to infections.
Thus, damage to bone marrow can critically disrupt essential functions, potentially leading to life-threatening conditions.
Step 2
Suggest which chemical is likely to be the most successful in combining with bcl-2.
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Answer
Chemical 2 is likely to be the most successful in combining with bcl-2.
Step 3
Give a reason for your choice.
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Answer
Chemical 2 has a shape that will combine exactly with bcl-2, making it structurally compatible. This is crucial for effective binding and mimicking the action of BH3, making it a promising candidate for treatment.