Mosunetuzumab is a bispecific monoclonal antibody - VCE - SSCE Biology - Question 28 - 2023 - Paper 1
Question 28
Mosunetuzumab is a bispecific monoclonal antibody. Bispecific antibodies are designed to simultaneously bind to two different targets, such as a cancer cell antigen ... show full transcript
Worked Solution & Example Answer:Mosunetuzumab is a bispecific monoclonal antibody - VCE - SSCE Biology - Question 28 - 2023 - Paper 1
Step 1
A. lacks a constant region.
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Answer
This option is incorrect. A constant region is essential for the stability and overall function of antibodies.
Step 2
B. contains only heavy chains.
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Answer
This option is not correct as antibodies typically contain both heavy and light chains.
Step 3
C. contains both a light and a heavy chain.
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Answer
While this is true for many antibodies, it does not specifically contribute to the bispecificity of mosunetuzumab.
Step 4
D. has two different-shaped variable regions.
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Answer
This is the correct answer. The unique feature of mosunetuzumab is that it has two different variable regions, allowing it to bind simultaneously to two different targets.
