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A common neurotransmitter is acetylcholine (ACh), which excites the post-synaptic neuron - VCE - SSCE Biology - Question 18 - 2011 - Paper 1

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A common neurotransmitter is acetylcholine (ACh), which excites the post-synaptic neuron. Lack of ACh in brain synapses has been linked to Alzheimer’s disease. A num... show full transcript

Worked Solution & Example Answer:A common neurotransmitter is acetylcholine (ACh), which excites the post-synaptic neuron - VCE - SSCE Biology - Question 18 - 2011 - Paper 1

Step 1

a. administer esrine as a drug

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Answer

Administering esrine could inhibit acetylcholinesterase, thereby preventing the breakdown of ACh. This would increase levels of ACh in the synapse, possibly improving transmission and alleviating symptoms of Alzheimer’s.

Step 2

b. inject curare into the patient’s CNS

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Answer

Injecting curare would block post-synaptic receptors and would likely worsen symptoms by preventing ACh from exerting its effects, making it an inappropriate treatment.

Step 3

c. recommend that the patient stop smoking

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Answer

Recommending that the patient stop smoking does not directly address the acetylcholine deficiency associated with Alzheimer’s, so its effectiveness as a treatment is unclear.

Step 4

d. purposely infect the patient with Clostridium

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Answer

Infecting the patient with Clostridium would lead to decreased levels of ACh, further exacerbating Alzheimer’s symptoms. This option is not a viable treatment.

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