A fragment of DNA from chromosome 7 of each of two persons, Smith and Moore, are sequenced - VCE - SSCE Biology - Question 15 - 2012 - Paper 1
Question 15
A fragment of DNA from chromosome 7 of each of two persons, Smith and Moore, are sequenced. The nucleotide sequences in corresponding regions are shown below. This D... show full transcript
Worked Solution & Example Answer:A fragment of DNA from chromosome 7 of each of two persons, Smith and Moore, are sequenced - VCE - SSCE Biology - Question 15 - 2012 - Paper 1
Step 1
A. the complement of Smith's DNA strand would have the sequence
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Answer
The complement of a DNA strand can be determined by replacing each nucleotide with its complement: A with T, T with A, C with G, and G with C. Thus, the complement of Smith's sequence (G A T G G A T C G A G G T C) would be C T A C C T A G C T C C A G, not matching the provided sequence.
Step 2
B. the amino acid sequence in the polypeptides translated from the DNA of Moore and of Smith would be identical.
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Without knowing the specifics of the codons translated from both sequences, we cannot conclude that they will be identical. Any variation in the nucleotide sequence could lead to a different amino acid sequence due to the redundancy of the genetic code.
Step 3
C. the mRNA transcribed from Smith's DNA would have the sequence
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The mRNA transcribed from Smith's DNA would be complementary to the DNA template strand. The corresponding mRNA sequence would be C U A C C U A G C U C C A G, derived from the original DNA sequence.
Step 4
D. Moore's genetic disorder could be due to a deletion of one of the nucleotides.
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Since Moore exhibits a genetic disorder and has a slightly different nucleotide sequence than Smith, this variation could be the result of a deletion or other mutation that potentially disrupts normal enzyme function, supporting the idea of a genetic disorder linked to nucleotide changes.