Bradykinin is a peptide that lowers blood pressure - VCE - SSCE Chemistry - Question 8 - 2011 - Paper 1
Question 8
Bradykinin is a peptide that lowers blood pressure.
Diagram I shows the amino acid sequence of bradykinin..
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
diagram I
Diagram ... show full transcript
Worked Solution & Example Answer:Bradykinin is a peptide that lowers blood pressure - VCE - SSCE Chemistry - Question 8 - 2011 - Paper 1
Step 1
a. On diagram I, circle the section of bradykinin that is represented in diagram II.
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Answer
To identify the section of bradykinin represented in diagram II, locate the segment that includes the amino acids and linkages shown in diagram II. This consists of the amino acids Gly and Ser from the sequence Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg.
Step 2
b. Identify the two functional groups that are formed as a result of the hydrolysis of the peptide link.
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Answer
During hydrolysis of a peptide bond, two functional groups are formed: the amino group (NH2) and the carboxyl group (COOH). These groups characterize the resulting amino acids.
Step 3
c. Draw the chemical structure, showing all bonds, of the amino acid glycine as it would exist in solution at pH = 1.
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Answer
The chemical structure of glycine at pH = 1 can be represented as follows:
H
|
H2N—C—COOH
|
H
In this presentation, the amino group (NH3+) is protonated, and the carboxyl group (COOH) remains intact.