Bradykinin is a peptide that lowers blood pressure - VCE - SSCE Chemistry - Question 8 - 2011 - Paper 1
Question 8
Bradykinin is a peptide that lowers blood pressure.
Diagram I shows the amino acid sequence of bradykinin..
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
digram I
D... show full transcript
Worked Solution & Example Answer:Bradykinin is a peptide that lowers blood pressure - VCE - SSCE Chemistry - Question 8 - 2011 - Paper 1
Step 1
a. On diagram I, circle the section of bradykinin that is represented in diagram II.
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Answer
The section of bradykinin represented in diagram II corresponds to the amino acid sequence 'Ser'. This can be identified in diagram I, as it is the part of the sequence where the structure includes the hydroxyl (-OH) group.
Step 2
b. Identify the two functional groups that are formed as a result of the hydrolysis of the peptide link.
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Answer
Upon hydrolysis of the peptide link in bradykinin, the two functional groups formed are:
Amino group (–NH₂), which is characteristic of amino acids.
Carboxyl group (–COOH), which is typically present in amino acids.
Step 3
c. Draw the chemical structure, showing all bonds, of the amino acid glycine as it would exist in solution at pH = 1.
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Answer
The chemical structure of glycine at pH = 1, showing all bonds, is represented as follows:
H O H
\\ || \
H₂N—C—C—OH
//
H
At this pH, the amino group is protonated, leading to the structure where the amino group is positively charged.