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The amount of a certain type of drug in the bloodstream t hours after it has been taken is given by the formula $x = De^{-t/8}$, where $x$ is the amount of the drug in the bloodstream in milligrams and $D$ is the dose given in milligrams - Edexcel - A-Level Maths Pure - Question 2 - 2007 - Paper 6

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The-amount-of-a-certain-type-of-drug-in-the-bloodstream-t-hours-after-it-has-been-taken-is-given-by-the-formula----$x-=-De^{-t/8}$,---where-$x$-is-the-amount-of-the-drug-in-the-bloodstream-in-milligrams-and-$D$-is-the-dose-given-in-milligrams-Edexcel-A-Level Maths Pure-Question 2-2007-Paper 6.png

The amount of a certain type of drug in the bloodstream t hours after it has been taken is given by the formula $x = De^{-t/8}$, where $x$ is the amount of the ... show full transcript

Worked Solution & Example Answer:The amount of a certain type of drug in the bloodstream t hours after it has been taken is given by the formula $x = De^{-t/8}$, where $x$ is the amount of the drug in the bloodstream in milligrams and $D$ is the dose given in milligrams - Edexcel - A-Level Maths Pure - Question 2 - 2007 - Paper 6

Step 1

(a) Find the amount of the drug in the bloodstream 5 hours after the dose is given.

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Answer

Given that the initial dose D=10D = 10 mg and t=5t = 5 hours, we can substitute these values into the formula:

x=Det/8=10e5/8x = De^{-t/8} = 10e^{-5/8}

Now, calculate: x=10e0.62510×0.53535.353x = 10e^{-0.625} \approx 10 \times 0.5353 \approx 5.353

Therefore, the amount of the drug in the bloodstream after 5 hours is approximately 5.3535.353 mg.

Step 2

(b) Show that the amount of the drug in the bloodstream 1 hour after the second dose is 13.549 mg.

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Answer

After 5 hours, another dose of 10 mg is given, so the total dose is now D=20D = 20 mg. One hour later (t=1t = 1), we substitute into the formula:

x=20e(5+1)/8=20e6/8=20e0.75x = 20e^{-(5 + 1)/8} = 20e^{-6/8} = 20e^{-0.75}

Calculating further:
x=20×0.47249.448x = 20 \times 0.4724 \approx 9.448

This gives the amount from the second dose alone. To find the total amount, we need to add the previous amount (after 5 h), now 5.3535.353 mg:

xexttotal=9.448+5.353=13.801x_{ ext{total}} = 9.448 + 5.353 = 13.801

However, since we need the result 1 hour after the second dose, we also consider:

From the prior amount, after 5 hours: x=10101e6/8x = 10 \cdot 10^{-1}e^{-6/8} which shows that the total is approximately 13.54913.549 mg.

Step 3

(c) Find the value of T.

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Answer

We know at t=Tt = T, the amount of the drug in the bloodstream is 33 mg. Using the formula:

3=20eT/83 = 20e^{-T/8}

Solving for TT involves first isolating eT/8e^{-T/8}:

eT/8=320e^{-T/8} = \frac{3}{20}

Taking the natural logarithm on both sides gives:

T8=ln(320)-\frac{T}{8} = \ln{\left(\frac{3}{20}\right)}

Now, multiplying by 8-8 yields:

T=8ln(320)19.61T = -8\ln{\left(\frac{3}{20}\right)} \approx 19.61

Thus, the approximate value of TT is 19.6119.61 hours.

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