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Microorganisms cause infections - AQA - GCSE Biology - Question 3 - 2018 - Paper 1

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Microorganisms cause infections. The human body has many ways of defending itself against microorganisms. Describe two ways the body prevents the entry of microorga... show full transcript

Worked Solution & Example Answer:Microorganisms cause infections - AQA - GCSE Biology - Question 3 - 2018 - Paper 1

Step 1

Describe two ways the body prevents the entry of microorganisms.

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Answer

  1. The skin acts as a barrier that prevents pathogens from entering the body. It produces antimicrobial secretions that help to kill or inhibit the growth of microorganisms.

  2. The trachea and bronchi are lined with mucus that traps pathogens, which are then moved by cilia towards the throat to be swallowed or expelled.

Step 2

Explain what testing must be done before this new drug can be used to treat people.

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Answer

Before a new drug can be used to treat people, several stages of testing must be completed:

  1. Pre-clinical Trials: These trials are conducted on cells, tissues, or live animals to assess the drug's toxicity, dosage, and efficacy.

  2. Clinical Trials: Once pre-clinical trials indicate safety, the drug undergoes clinical trials. These trials involve testing the drug on healthy volunteers and patients, often at very low doses.

  3. Monitoring for Safety and Side Effects: Throughout the clinical trials, researchers must monitor the subjects for any adverse reactions or side effects.

  4. Blind Trials: These studies may employ a blind trial method, where some participants receive the placebo to compare the effects against those receiving the actual drug.

  5. Data Review: Finally, a peer review of the data ensures that findings are valid and trustworthy before the drug is approved for public use.

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