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Figure 5 shows how alcohol consumption increases the risk of developing liver cancer - Edexcel - GCSE Biology Combined Science - Question 4 - 2021 - Paper 1

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Figure 5 shows how alcohol consumption increases the risk of developing liver cancer. Someone who does not drink alcohol has a 1.0 risk of developing liver cancer. ... show full transcript

Worked Solution & Example Answer:Figure 5 shows how alcohol consumption increases the risk of developing liver cancer - Edexcel - GCSE Biology Combined Science - Question 4 - 2021 - Paper 1

Step 1

Calculate the risk of developing liver cancer for someone who consumes 4 units of alcohol a day.

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Answer

To find the risk for someone consuming 4 units of alcohol:

  1. Calculate the total grams of alcohol: 4 units×8 grams/unit=32 grams4 \text{ units} \times 8 \text{ grams/unit} = 32 \text{ grams}

  2. Using the graph, determine the corresponding risk of developing liver cancer for 32 grams:

    • From Figure 5, the risk is approximately 1.2.

Therefore, the risk of developing liver cancer for someone who consumes 4 units of alcohol a day is 1.2.

Step 2

Describe how cancer develops in the liver.

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Answer

Cancer development in the liver can involve several processes:

  1. Mutations in DNA: Genetic mutations can occur due to various factors, leading to changes in the normal function of the cells.

  2. Uncontrolled Cell Division: The mutated cells may begin dividing uncontrollably.

  3. Tumor Formation: This leads to a mass of cells, also known as a tumor, which can interfere with the normal function of the liver.

Step 3

Give two safety precautions needed when blood is removed from this person.

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Answer

  1. Wear gloves: This helps prevent contamination and protects both the healthcare provider and the patient.

  2. Use a sterile needle: Ensures that the blood is taken safely without introducing infections.

Step 4

State and explain the genotype of female Z.

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Answer

The genotype of female Z is heterozygous (Hh).

This means she carries one dominant allele (H) and one recessive allele (h). Her offspring's possibilities indicate that at least one must have inherited the recessive allele for haemochromatosis.

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