Sickle cell disease is caused by a change in one of the bases coding for an amino acid on chromosome 11 - Edexcel - GCSE Biology - Question 4 - 2016 - Paper 1
Question 4
Sickle cell disease is caused by a change in one of the bases coding for an amino acid on chromosome 11.
(a) Complete the sentence by putting a cross (✗) in the box... show full transcript
Worked Solution & Example Answer:Sickle cell disease is caused by a change in one of the bases coding for an amino acid on chromosome 11 - Edexcel - GCSE Biology - Question 4 - 2016 - Paper 1
Step 1
Complete the sentence by putting a cross (✗) in the box next to your answer.
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Answer
The part of the cell that contains chromosome 11 is the C nucleus. The nucleus is the control center of the cell and houses the genetic material, including chromosomes.
Step 2
Complete the genetic diagram to show the possible genotypes from two heterozygous parents.
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Answer
In the Punnett square for two heterozygous parents (Ff x Ff), the possible genotypes are: 25% FF, 50% Ff, and 25% ff. This means there are three carriers (Ff) out of four possible offspring.
Step 3
Calculate the percentage probability that the offspring will be carriers of the sickle cell allele but not have sickle cell disease.
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Answer
The percentage probability that the offspring will be carriers (Ff) but not have sickle cell disease (ff) is 50%. Since Ff represents carriers, the calculation is as follows: out of four offspring, two (Ff) are carriers. Thus, the calculation is: rac{2}{4} imes 100 = 50 ext{%}.
