Haemophilia is a recessive sex-linked disorder - Edexcel - GCSE Biology - Question 1 - 2014 - Paper 1
Question 1
Haemophilia is a recessive sex-linked disorder.
This family pedigree shows the inheritance of haemophilia.
(a) (i) State the sex chromosomes of person B.
(ii) Exp... show full transcript
Worked Solution & Example Answer:Haemophilia is a recessive sex-linked disorder - Edexcel - GCSE Biology - Question 1 - 2014 - Paper 1
Step 1
State the sex chromosomes of person B.
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Answer
Person B has the sex chromosomes XX. This indicates that person B is female and does not have the haemophilia allele, as it is located on the X chromosome.
Step 2
Explain why the male offspring from A and B do not have haemophilia.
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Answer
The male offspring from A and B do not have haemophilia because:
Male offspring inherit their X chromosome from their mother (B) and a Y chromosome from their father (A). Since B is a carrier but not affected, she can pass on an unaffected X chromosome.
A is affected by haemophilia and contributes a Y chromosome. Therefore, the male offspring receive an unaffected X from B and a Y from A, resulting in them not having the disorder.