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The diagram shows a strand of mRNA undergoing splicing - Scottish Highers Human Biology - Question 4 - 2022

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The diagram shows a strand of mRNA undergoing splicing. Y Z Y Z Y Z Y primary mRNA transcript Y Y Y Y mature mRNA transcript (a) Name the regions labelled Y. ... show full transcript

Worked Solution & Example Answer:The diagram shows a strand of mRNA undergoing splicing - Scottish Highers Human Biology - Question 4 - 2022

Step 1

Name the regions labelled Y.

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Answer

Exons

Step 2

Calculate how many amino acids are present in the protein coded for by the mature transcript.

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Answer

To find the number of amino acids, we start with the primary transcript's total bases and account for the removed bases. The mature mRNA transcript has:

Total bases = 3150 - 600 = 2550.

Each amino acid is coded by three bases.

Thus, the number of amino acids is:

Amino Acids=25503=850\text{Amino Acids} = \frac{2550}{3} = 850

However, we subtract 1 due to the stop codon, resulting in a total of 848 amino acids.

Step 3

Name the process that results in different proteins being expressed from a single gene.

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Answer

Alternative RNA splicing.

Step 4

Describe how this process leads to the formation of different proteins.

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Answer

Alternative splicing allows for different exons to be included or excluded from the final mRNA transcript. As a result, different combinations of exons can code for various proteins. This variation leads to a diversity of proteins that can perform different functions, even though they originate from the same gene.

Step 5

Describe the effect that this mutation has had on the mature mRNA transcript.

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Answer

The mutation has resulted in the retention of at least one intron within the mature mRNA transcript, meaning not all introns have been removed.

Step 6

Suggest how this mutation may affect the structure of the protein formed.

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Answer

The protein will likely not fold properly due to the presence of extra bases that were part of the intron. This abnormal sequence could affect the protein's shape and length, possibly leading to a nonfunctional protein.

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