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Structure of the Genome Simplified Revision Notes

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Biology

Structure of the Genome

Genome Structure

Structure of the Genome

Introduction

  • The genome is the complete set of genetic material in an organism.
  • It contains all the information needed for an organism's growth, development, and function.

Genome Composition

  • The genome is composed of DNA (deoxyribonucleic acid).
  • DNA is a long, double-stranded molecule made up of nucleotides.
  • Nucleotides consist of a sugar (deoxyribose), a phosphate group, and one of four nitrogenous bases (adenine, thymine, guanine, or cytosine).

Chromosomes

  • DNA is organised into structures called chromosomes.
  • In humans, there are 46 chromosomes, grouped into 23 pairs.
  • Chromosomes are located within the nucleus of a cell.
  • They contain genes, which are segments of DNA that code for specific proteins.

Genes and Protein Synthesis

  • Genes are the functional units of the genome.
  • They provide instructions for synthesising proteins.
  • Proteins play crucial roles in various cellular processes and determine an organism's traits.

Structure of the Genome

Non-Coding DNA

  • Not all DNA encodes proteins; a significant portion is non-coding.
  • Non-coding DNA has regulatory functions, controlling when and where genes are expressed.
  • Some non-coding regions are repetitive sequences, with unknown functions.

Genome Size

  • Genome size varies among species.
  • Some organisms have relatively small genomes, while others have large, complex genomes.
  • The number of genes does not always correlate with genome size.

Summary

The genome is the complete set of genetic material in an organism, composed of DNA. DNA is organised into chromosomes, which contain genes that provide instructions for protein synthesis. Non-coding DNA regulates gene expression. Genome size varies among species, and it is not solely determined by the number of genes. Understanding the genome is fundamental to studying genetics and biology.

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