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Explain how a resting potential is maintained across the axon membrane in a neurone - AQA - A-Level Biology - Question 2 - 2021 - Paper 2

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Explain how a resting potential is maintained across the axon membrane in a neurone. Explain why the speed of transmission of impulses is faster along a myelinated... show full transcript

Worked Solution & Example Answer:Explain how a resting potential is maintained across the axon membrane in a neurone - AQA - A-Level Biology - Question 2 - 2021 - Paper 2

Step 1

Explain how a resting potential is maintained across the axon membrane in a neurone.

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Answer

To maintain a resting potential, there is a higher concentration of potassium ions (K") inside the neurone and a higher concentration of sodium ions (Na") outside.

  1. Ion Diffusion: Potassium ions diffuse out of the neurone, while sodium ions are less permeable and do not easily enter. This creates a negative charge inside the neurone.

  2. Membrane Permeability: The axon membrane is more permeable to potassium ions than sodium ions, leading to the net movement of K" ions out, which contributes to the negative resting potential.

  3. Active Transport: The sodium-potassium pump actively transports sodium ions out and potassium ions in, maintaining the ion gradients essential for resting potential.

Step 2

Explain why the speed of transmission of impulses is faster along a myelinated axon than along a non-myelinated axon.

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Answer

Myelination provides electrical insulation, allowing for:

  1. Saltatory Conduction: In myelinated axons, action potentials jump from one node of Ranvier to the next, significantly increasing the speed of impulse transmission compared to the continuous conduction in non-myelinated axons.

  2. Electrical Insulation: The myelin sheath minimizes ion leakage and reduces capacitance, enabling quicker depolarization and repolarization processes at the nodes.

  3. Distance Efficiency: Non-myelinated axons experience slower transmission because the entire length of the axon must undergo depolarization.

Step 3

Explain why.

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Answer

The addition of a respiratory inhibitor affects the neurone's energy supply:

  1. No ATP Production: The inhibitor leads to a lack of ATP, which is crucial for the sodium-potassium pump to function.

  2. No Active Transport: Without ATP, the pump cannot extrude Na" from inside the cell and cannot take K" in, resulting in an equalization of ion concentrations.

  3. Electrical Gradient Disruption: As Na" accumulates inside and K" is not brought back in, the neurone's resting potential decreases, resulting in the observed change from -70 mV to 0 mV.

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