Mutagens (HSC SSCE Biology): Flashcards

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Mutagens
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Mutagen definition

Environmental agent that can alter DNA and cause mutations

Mutagenesis definition

Process of inducing mutations through external agents

Three main categories of mutagens

Chemical, naturally occurring, and physical mutagens

Examples of chemical mutagens

Alcohol, tar in tobacco smoke, benzene, asbestos

How nitrosamine forms

Forms in stomach when nitrites combine with amines

Pyrimidine dimers

Adjacent thymine or cytosine bases bonded together by UV

Ionising radiation

Radiation with enough energy to break chemical bonds in DNA

Free radicals from ionising radiation

Produced when high-energy electrons interact with water

Base excision repair

Damaged base removed from sugar linkage and replaced

Mismatch repair

DNA polymerase checks and corrects replication errors

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