Accuracy in DNA Replication (HSC SSCE Biology): Flashcards
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Practise the cards
10 cards from this deck
Replication fidelity
Replication fidelity
Accuracy with which DNA is copied
Two reasons DNA accuracy is critical
Two reasons DNA accuracy is critical
Heredity and gene expression
Spontaneous mutations
Spontaneous mutations
Natural random mistakes during DNA replication
Mutagenic mutations
Mutagenic mutations
Errors from environmental factors damaging DNA
Mutagens
Mutagens
Environmental factors that change DNA (radiation, chemicals)
Three steps of DNA mismatch repair
Three steps of DNA mismatch repair
Recognition, excision, replacement
Enzyme that performs DNA mismatch repair
Enzyme that performs DNA mismatch repair
DNA polymerase I
When mutations become permanent
When mutations become permanent
When undetected during next replication cycle
Cell cycle phase when DNA replication occurs
Cell cycle phase when DNA replication occurs
S phase (synthesis)
How DNA errors can lead to cancer
How DNA errors can lead to cancer
Errors in cell cycle control genes cause uncontrolled division