The KRAS gene codes for a protein called K-Ras - AQA - A-Level Biology - Question 8 - 2023 - Paper 2
Question 8
The KRAS gene codes for a protein called K-Ras. The protein relays signals from outside a cell's nucleus, stimulating cell division. An alteration in the KRAS gene p... show full transcript
Worked Solution & Example Answer:The KRAS gene codes for a protein called K-Ras - AQA - A-Level Biology - Question 8 - 2023 - Paper 2
Step 1
Mutation in KRAS gene
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Answer
An alteration in the KRAS gene often begins with a mutation that changes the base sequence of the gene. This mutation can result in the production of a faulty or overactive K-Ras protein.
Step 2
Increased Signalling by K-Ras
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Answer
The mutated K-Ras protein may function as an active signaling molecule, leading to increased cell signaling pathways that stimulate uncontrollable cell division.
Step 3
Uncontrolled Cell Division
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Answer
As a result of the mutation and increased signaling, there is a disruption in the regulation of the cell cycle, leading to rapid and uncontrollable cell division, which can ultimately result in the formation of tumors.
