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The Refractory Period Simplified Revision Notes

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6.2.4 The Refractory Period

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The refractory period is a short period after an action potential when a neurone membrane cannot be excited again. This occurs because sodium ion channels are in a recovery state, and the membrane needs to return to its resting potential before it can respond to another stimulus.

Key Features of the Refractory Period

  1. Phases of the Refractory Period:
  • Absolute Refractory Period:
  • During this phase, no action potential can be generated, regardless of the strength of the stimulus.
  • This occurs because the sodium ion channels remain closed, preventing depolarisation.
  • Relative Refractory Period:
  • During this phase, a new action potential can be generated, but only if the stimulus is much stronger than usual.
  • This is because the membrane is still hyperpolarised.
  1. Functions of the Refractory Period:
  • Ensures that action potentials travel in one direction only by preventing the propagation of a backward impulse.
  • Produces discrete impulses by ensuring that each action potential is separate from the next.
  • Limits the frequency of nerve impulses, ensuring the neurone has time to recover.
  1. The All-or-Nothing Principle:
  • An action potential is only generated if the stimulus reaches a threshold value.
  • If the threshold is not reached, no action potential is produced.
  • All action potentials generated have the same magnitude, regardless of stimulus strength.
infoNote

Exam Tip

  • Be able to distinguish between the absolute and relative refractory periods.
  • Highlight the role of the refractory period in unidirectional flow of nerve impulses.
  • Understand how the all-or-nothing principle contributes to consistent signalling.
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