Discovery & Development of Drugs (OCR GCSE Biology A, Combined (Gateway Science Suite)): Flashcards

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Discovery & Development of Drugs
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Where were many drugs initially discovered?

Plants and microorganisms

3 things drugs are tested for

Toxicity, efficacy, and dose

Efficacy (in drug testing)

How well they carry out their role

Use of aspirin

Painkiller

Origin of aspirin

Willow

Use of digitalis

Treats heart problems

Origin of digitalis

Foxgloves

Discoverer of penicillin

Alexander Fleming

Mould that produces penicillin

Penicillium mould

What preclinical testing uses

Cells, tissues, and live animals

Placebo

Looks like drug but has no active ingredient, no effect

Double-blind trial

Neither patient nor doctor knows who receives the drug

Purpose of peer review

Check for repeatability

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