Uses of Monoclonal Antibodies (OCR GCSE Biology A (Gateway Science Suite)): Flashcards

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Uses of Monoclonal Antibodies
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Hormone detected in pregnancy tests

Human chorionic gonadotrophin (hCG)

What mobile antibodies attach to in pregnancy tests

Blue beads

Type of antibodies in 2nd section of pregnancy test

Stationary antibodies complementary to hCG

Blue line in pregnancy test means

Pregnant

What monoclonal antibodies bind to for lab monitoring

Fluorescent dye

Example of monoclonal antibody use in blood screening

Screening donated blood for HIV infections

Antigens on cancer cell membranes

Tumour markers

Cancer treatment method 1 with monoclonal antibodies

Bind to tumour markers to stimulate immune system attack

Cancer treatment method 2 with monoclonal antibodies

Bind to receptor sites, stop cell division

Cancer treatment method 3 with monoclonal antibodies

Transport toxic drugs/chemicals/radioactive substances

Advantage: monoclonal antibodies specificity

Only bind specific cells, healthy cells not affected

Advantage: monoclonal antibodies flexibility

Can be engineered to treat many conditions

Disadvantage: cost of monoclonal antibodies

Expensive to develop

Disadvantage of using mouse lymphocytes

Triggered immune response in patients

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