Sex Linkage (Leaving Cert Biology): Flashcards

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Sex Linkage
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Sex linkage definition

Gene located on a sex chromosome

Female sex chromosomes

XX

Male sex chromosomes

XY

Red-green colour blindness trait

Inability to distinguish between red and green

Haemophilia trait

Inability to form blood clots properly

Why are sex-linked traits more common in males?

Males need only one recessive gene on X to express trait

Genes needed for females to express sex-linked trait

Two recessive genes (one on each X chromosome)

Carrier female definition

Heterozygous female with one normal and one abnormal allele

Male with normal vision genotype (N=normal)

XN Y

Female with normal vision genotype

XN XN

Female carrier genotype (N=normal, n=colour blind)

XN Xn

Male with colour blindness genotype

Xn Y

Female with colour blindness genotype

Xn Xn

Chromosome with most sex-linked genes

X chromosome

Offspring % from carrier female × normal male cross

25% each: normal female, carrier, normal male, colour blind male

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