The Specific Defence System (The Immune System) (Leaving Cert Biology): Flashcards

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The Specific Defence System (The Immune System)
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Definition of an antigen

A surface protein that stimulates antibody production

Definition of an antibody

Protein made by lymphocytes in response to an antigen

When specific defence system activates

When microorganisms get past general defence system

White blood cells in immune organs

Lymphocytes and monocytes

Where antigens are found

Bacterial walls, viral coats, cancerous/foreign cells

What monocytes do to pathogens

Surround and digest them

What monocytes display after digesting pathogen

The antigens on their outer surface

Antibody-antigen specificity

Each antibody is specific to one antigen

How antibodies prevent entry

Stop bacteria/viruses entering cells for phagocyte attack

How antibodies work via clumping

Clump antigen cells for easier phagocyte destruction

How antibodies trigger complement system

Activate it to cause pathogen cells to burst

Antibody production time on 2nd exposure

5 days instead of 14 days

Why multiple cold/flu infections possible

Different antigens need different antibodies

What are autoimmune diseases

Body produces antibodies against its own tissues

Rheumatoid arthritis target

Joints, causing inflammation and pain

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