Diseases Caused by Protista and Fungi (Grade 11 NSC Matric Life Sciences): Revision Notes
Diseases Caused by Protista and Fungi
Understanding diseases caused by protista and fungi is essential for recognising how these microscopic organisms impact human health, animal welfare, and agricultural productivity. This section explores the major diseases caused by protozoans and fungi, their transmission methods, symptoms, and management strategies.
Diseases caused by protista
Malaria
Malaria represents one of the most serious health threats globally, particularly affecting people living in warm, humid regions of the world. This life-threatening condition demonstrates how protistan parasites can cause devastating illness in human populations.
Causative agent and transmission
The disease results from infection by a protozoan parasite called Plasmodium vivax. The parasite reaches humans through the bite of infected female Anopheles mosquitoes, which serve as the disease vector.
A vector is an organism that transports disease-causing pathogens from one infected host to another healthy host. In malaria, the mosquito acts as both a host for the parasite and a delivery system to humans.
The malaria parasite follows a complex life cycle that requires two different hosts - mosquitoes and humans - to complete its development successfully. This dual-host requirement makes the disease particularly challenging to control.

Symptoms and effects
Early malaria symptoms often resemble common flu, making initial diagnosis difficult.
Typical Malaria Symptom Progression:
Early symptoms (resembling flu):
- High fever accompanied by severe shivering
- Intense headaches that persist
- Joint and muscle pain throughout the body
- Nausea and vomiting
- Progressive weakness and fatigue
Advanced symptoms (without treatment):
- Anaemia (reduced red blood cell count)
- Possible seizures in severe cases
- Potential coma and organ damage
Without prompt medical treatment, malaria can progress rapidly. Patients may fall into a coma as the parasite damages vital organs, potentially leading to death.
Economic impact
Malaria creates significant economic hardship in affected communities:
- Families lose income when breadwinners become too ill to work or die from the disease, pushing households into poverty
- Treatment costs place heavy financial burdens on families, particularly in developing nations where healthcare access is limited and expensive
Management and prevention strategies
The most effective approach to malaria control focuses on preventing mosquito bites in areas where the disease occurs:
- Stay indoors during peak mosquito activity times (between sunset and sunrise)
- Install fine mesh screens on doors and windows to prevent mosquitoes entering homes
- Sleep under treated mosquito nets that provide physical protection
- Apply insect repellent products to exposed skin areas
- Wear long-sleeved clothing and long trousers when outdoors during evening hours
- Remove standing water sources where mosquitoes breed, such as blocked drains, old containers, and stagnant ponds
Medical interventions
Anti-malarial medications can be taken preventively before travelling to malaria-endemic areas. Effective drugs are also available for treating people who contract the infection.
Government health programmes play crucial roles by establishing medical clinics and controlling mosquito populations through targeted spraying with insecticides like DDT.
Diseases caused by fungi
Fungal infections affect both plants and animals, causing significant agricultural losses and health problems. Unlike bacterial or viral infections, fungal diseases often develop slowly and can persist for extended periods.
Rusts
Plant rust diseases represent a major threat to agricultural crops and ornamental plants worldwide. These fungal infections cause substantial economic losses in farming communities.

Description and plant damage
Rusts comprise a group of fungi that specifically target crop plants including tomatoes and beans, grass species, and flowering plants such as roses, hollyhocks, and snapdragons. The fungal structures called hyphae penetrate deep into plant tissues, gradually destroying healthy cells and disrupting normal plant functions.
Infected plants develop characteristic bright orange, raised spots on leaf surfaces that resemble rusty metal deposits. These orange structures contain thousands of fungal spores ready for dispersal to new host plants.
Management and treatment strategies
Effective rust control requires multiple approaches:
- Select and plant crop varieties that show natural resistance to rust infections
- Maintain plant health through proper nutrition by adding appropriate fertilisers to soil or water systems
- Clean and sterilise gardening equipment, especially pruning tools, between uses to prevent spore transfer
- Apply chemical fungicides (anti-fungal treatments) when infections are detected
- Remove and burn infected plant material immediately to prevent spore spread to healthy plants
Thrush
Thrush infections occur when yeast fungi multiply excessively in the human body, particularly in warm, moist environments that these organisms favour.
Causative agent and types
The yeast Candida albicans causes thrush infections. While this fungus normally lives harmlessly on human skin and in body cavities, certain conditions allow it to multiply rapidly and cause problems.
Thrush commonly develops in moist body areas including the mouth, vaginal region, and upper digestive system.
Types of Thrush Infections:
Oral thrush:
- Appears as thick, white patches covering the tongue and inside mouth surfaces
- Causes difficulty eating and uncomfortable burning sensations
- Common in bottle-fed and breast-fed babies, and people wearing poorly fitting dentures
Vaginal thrush:
- Commonly affects pregnant women and those using hormonal contraceptives
- Worsened by tight-fitting clothing and synthetic underwear
- Symptoms include severe itching, burning during urination, and greyish-white vaginal discharge
Risk factors
Several conditions increase thrush susceptibility:
- Weakened immune systems due to HIV/AIDS or cancer chemotherapy treatments
- Diabetes - Candida thrives in high blood sugar environments
- Excess weight creating moist skin folds where fungi multiply
- Babies wearing wet nappies for prolonged periods
- Poor general health from stress, inadequate sleep, and high-sugar diets
- Extended antibiotic use that disrupts normal bacterial balance
Management approaches
Thrush management focuses on reducing conditions that encourage fungal growth:
- Wear loose-fitting, breathable clothing made from natural fibres, especially cotton underwear
- Avoid perfumed soaps and bubble bath products that irritate sensitive areas
- Maintain a balanced diet low in refined sugars and processed foods
- Take probiotic supplements when using antibiotics for extended periods
- Treat oral thrush with anti-fungal mouthwash solutions
- Apply anti-fungal creams to affected skin areas
- Severe cases may require systemic treatment with oral anti-fungal medications
- Ensure dentures fit properly and maintain strict cleaning routines
Ringworm
Despite its name, ringworm results from fungal infection rather than parasitic worms. This condition affects both humans and animals, making it a significant public health concern.
Description and transmission
Fungal spores survive on skin surfaces of humans and animals, spreading easily through direct contact with infected individuals or pets. Household pets often serve as infection sources within families.
Symptoms and treatment
The infection creates distinctive circular, itchy patches on skin surfaces. These lesions typically appear raised above surrounding healthy skin with clearly defined borders.
Treatment strategies:
- Apply anti-fungal ointments directly to infected skin areas
- Treat all pets in the household to prevent re-infection
- Avoid sharing clothing, towels, or bedding with infected individuals
- Maintain strict hygiene practices including regular hand washing
Athlete's foot
This common fungal condition specifically targets foot areas, particularly spaces between toes and foot arch regions.
Causative agent and transmission environment
The fungus Tinea pedis causes athlete's foot infections. This organism thrives in warm, moist environments commonly found in public facilities.
The infection spreads easily when people walk barefoot in public areas such as communal showers, swimming pool changing areas, and sports facility locker rooms. The fungus feeds on keratin protein present in skin cells, causing the characteristic flaky, cracked skin appearance that allows bacterial infections to develop.
Key Points to Remember:
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Malaria is a life-threatening protistan disease spread by Anopheles mosquitoes - prevention focuses on avoiding mosquito bites through nets, repellents, and removing breeding sites
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Plant rusts are fungal diseases causing orange pustules on leaves - management includes resistant varieties, proper nutrition, and fungicide treatments
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Thrush results from Candida albicans overgrowth in moist body areas - prevention involves wearing breathable clothing, avoiding irritants, and maintaining good hygiene
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Ringworm creates circular skin lesions and spreads through direct contact - treat both humans and pets to prevent household transmission
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Athlete's foot thrives in warm, moist public areas - avoid walking barefoot in communal facilities and maintain proper foot hygiene