Mutations (Grade 12 NSC Matric Life Sciences): Flashcards

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Mutations
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Mutation definition

Permanent change to DNA within a cell

3 types of mutations by effect

Harmless, harmful, useful

% of DNA that is non-coding

98.5%

What harmful mutations alter

DNA sequences for producing proteins

Advantage of useful mutations

Better chance of survival in environment

When gene mutations occur

During DNA replication

Where sex-linked mutations occur

X chromosome

Shape of red blood cells in sickle cell anaemia

Sickle-shaped (curved like half-moon)

What chromosome aberrations involve

Changes to entire chromosomes

Cause of Down syndrome

Three copies of chromosome 21 (trisomy 21)

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