Regulation of Transcription & Translation (AQA A-Level Biology): Flashcards

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Regulation of Transcription & Translation
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What are transcription factors?

Proteins that regulate which genes are transcribed into mRNA

Where are transcription factors initially located?

Cytoplasm

What do activator transcription factors do?

Stimulate transcription by helping RNA polymerase bind

What do repressor transcription factors do?

Inhibit transcription by blocking RNA polymerase access

How does oestrogen regulate gene expression?

Acts as a steroid hormone that directly influences transcription

What is RNA interference (RNAi)?

Post-transcriptional mechanism preventing mRNA translation

How does siRNA control translation?

Cuts target mRNA into fragments that cannot be translated

How does miRNA control translation?

Blocks translation without cutting mRNA

Lac repressor when lactose absent

Binds to DNA and blocks transcription of enzyme gene

Lac repressor when lactose present

Cannot bind DNA; allows transcription of enzyme gene

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