Treatments for Schizophrenia (AQA A-Level Psychology): Flashcards
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What does drug therapy do for schizophrenia?
What does drug therapy do for schizophrenia?
Manages symptoms but does not cure
First antipsychotic drug & year introduced
First antipsychotic drug & year introduced
Chlorpromazine, 1952
Receptors blocked by typical antipsychotics
Receptors blocked by typical antipsychotics
D2 dopamine receptors
% with tardive dyskinesia (long-term typical use)
% with tardive dyskinesia (long-term typical use)
15%
Decade atypical antipsychotics emerged
Decade atypical antipsychotics emerged
1990s
Example of atypical antipsychotic
Example of atypical antipsychotic
Clozapine
Key advantage of atypical over typical drugs
Key advantage of atypical over typical drugs
Reduced movement-related side effects
% improved: antipsychotics vs placebo (Davis et al.)
% improved: antipsychotics vs placebo (Davis et al.)
70% vs 25%
% discontinuing meds within 18 months (Lieberman)
% discontinuing meds within 18 months (Lieberman)
74%
Side effects of atypical antipsychotics
Side effects of atypical antipsychotics
Weight gain, increased diabetes risk, metabolic problems