DNA Replication, Protein Synthesis, and Mutations (LC 2027) (Leaving Cert Biology): Flashcards

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DNA Replication, Protein Synthesis, and Mutations
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Central dogma flow of genetic information

DNA → RNA → Protein

Transcription definition

Transfer of genetic info from DNA to mRNA

RNA polymerase function

Enzyme that reads DNA and builds complementary mRNA

Base in RNA instead of thymine

Uracil (U)

Translation location

At ribosomes in the cytoplasm

Codon definition

Group of three bases on mRNA

tRNA function

Carries amino acids & has anticodon matching mRNA codon

Start codon sequence

AUG

mRNA function

Carries genetic info from nucleus to ribosomes

rRNA function

Forms part of ribosome structure with proteins

Mutation definition

Sudden change in amount or structure of DNA

Mutagen definition

External agent that increases rate of mutations

Point mutation characteristic

Changes in a single gene or small number of bases

Down syndrome chromosome count

47 chromosomes (extra chromosome 21)

CRISPR-Cas9 purpose

Gene editing tool to remove, add or alter DNA sequences

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