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10 cards from this deck
Damage to genes controlling mitosis & cell cycle
Group of abnormal cells continuously expanding
Malignant spread via metastasis, benign stay localised
Larger and darker due to abundant DNA
Proto-oncogenes
Slow cell division, repair DNA, trigger apoptosis
Oncogenes: activation; Tumour suppressors: inactivation
Silences them → increases cell division → tumour formation
p53 protein (involved in apoptosis)
Activates proto-oncogenes to become oncogenes in breast tissue
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