Gene Expression & Cancer (AQA A-Level Biology): Quizzes
📚Quizzes
Practise the questions
10 questions from this quiz
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Practise the questions
10 questions from this quiz
What type of genetic damage leads to cancer development?
What type of genetic damage leads to cancer development?
Damage to genes controlling mitosis
How does the growth rate of benign tumours compare to malignant tumours?
How does the growth rate of benign tumours compare to malignant tumours?
Benign tumours grow very slowly
What feature allows malignant tumours to spread through metastasis?
What feature allows malignant tumours to spread through metastasis?
Do not produce adhesion molecules
Why do malignant tumour cells often have larger and darker nuclei?
Why do malignant tumour cells often have larger and darker nuclei?
Due to abundant DNA
How do oncogenes develop?
How do oncogenes develop?
From mutations in proto-oncogenes
What is a key function of tumour suppressor genes?
What is a key function of tumour suppressor genes?
Trigger apoptosis in damaged cells
How do oncogenes and tumour suppressor genes differ in causing cancer?
How do oncogenes and tumour suppressor genes differ in causing cancer?
Oncogenes activated, suppressors inactivated
How does hypermethylation of promoter regions contribute to cancer?
How does hypermethylation of promoter regions contribute to cancer?
Silences tumour suppressor genes
What proportion of human cancers show abnormalities in the TP53 gene?
What proportion of human cancers show abnormalities in the TP53 gene?
More than half
How does oestrogen initially contribute to breast cancer development?
How does oestrogen initially contribute to breast cancer development?
Causes proto-oncogenes to become oncogenes