Genome Projects (AQA A-Level Biology): Flashcards

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Genome Projects
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Definition of a genome

Complete map of all genetic material in an organism

Definition of a proteome

All proteins produced by the genome

Number of base pairs in human genome

Over 3 billion base pairs

Number of genes in human genome

Approximately 20,000 genes

Definition of bioinformatics

Collecting and analysing complex biological data using computer algorithms

Modern genome sequencing technique

Whole-genome shotgun (WGS) sequencing

SNPs (Single nucleotide polymorphisms)

Single-base variations in the genome associated with diseases

First bacterium with fully sequenced genome (year)

Haemophilus influenza in 1995

Why prokaryotic proteomes easier to determine

Single circular DNA, no non-coding DNA portions

% of human genes that code for proteins

As few as 1.5%

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