Studies (Edexcel A-Level Psychology): Flashcards

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Van den Oever et al. (2008) Heroin-Seeking Relapse
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Van den Oever et al. study year

2008

Brain area studied for relapse mechanisms

Medial prefrontal cortex (mPFC)

Process changing AMPA receptors during relapse

Endocytosis

Receptors altered in cue-induced relapse

AMPA receptors

Training that stops drug-seeking behaviour

Extinction training

Active peptide effect on relapse behaviour

Reduced nose-poking/drug-seeking

Specific mPFC area blocking relapse

Ventral mPFC

Natural reinforcer unaffected by peptide

Sucrose

Learning theory explaining cue-triggered relapse

Classical conditioning

Potential treatment from blocking endocytosis

Pharmacological treatment

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