Discovery & Development of Drugs (AQA GCSE Biology): Flashcards

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Discovery & Development of Drugs
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Where many drugs were originally discovered

Plants and microorganisms

Three things new drugs must be tested for

Toxicity, efficacy, and dose

Definition of efficacy in drug testing

How well the drug carries out its role

What preclinical testing uses

Cells, tissues, and live animals

What clinical testing uses

Volunteers and patients

Drug from willow used as painkiller

Aspirin

Drug from foxgloves for heart problems

Digitalis

Scientist who discovered penicillin

Alexander Fleming

Mould that produces penicillin

Penicillium mould

What a placebo is

Appears like the drug but has no active ingredient or effect

Trial where only doctor knows who gets drug

Single-blind

Trial where neither patient nor doctor knows who gets drug

Double-blind

Why double-blind trials are used

To remove doctor bias when recording results

What peer review checks for

Repeatability

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