Uses of Monoclonal Antibodies (AQA GCSE Biology): Flashcards

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Uses of Monoclonal Antibodies
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What are 4 uses of monoclonal antibodies?

Pregnancy tests, lab measurements, research, disease treatment

Hormone in urine of pregnant women

Human chorionic gonadotrophin (hCG)

Mobile antibodies in pregnancy test attached to?

Blue beads

Stationary antibodies in pregnancy test

Stuck to stick, complementary to hCG

What does a blue line on pregnancy test indicate?

Pregnant

Monoclonal antibodies in labs bound to?

Fluorescent dye

Example of lab use of monoclonal antibodies

Screening donated blood for HIV infections

What are antigens on cancer cell membranes called?

Tumour markers

Monoclonal antibodies treat cancer by stimulating?

Immune system to attack cells

Monoclonal antibodies block what on cancer cells?

Receptor sites, stopping cell division

Monoclonal antibodies transport to cancer cells

Toxic drugs, chemicals or radioactive substances

Advantage: monoclonal antibodies only bind to?

Specific cells, healthy cells not affected

Monoclonal antibodies can be engineered for?

Many different conditions

Disadvantage of monoclonal antibodies - attachment

Difficult to attach to drugs

Disadvantage of monoclonal antibodies - cost

Expensive to develop

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