Discovery & Development of Drugs (OCR GCSE Biology A (Gateway Science Suite)): Flashcards

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Discovery & Development of Drugs
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Initial source of many drugs

Plants & microorganisms

Who synthesises most new drugs today

Chemists

3 things drugs must be tested for

Toxicity, efficacy & dose

Definition of efficacy

How well they carry out their role

What preclinical testing uses

Cells, tissues & live animals

Aspirin's use & origin plant

Painkiller; from willow

Digitalis's use & origin plant

Treats heart problems; from foxgloves

Discoverer of penicillin

Alexander Fleming

What produces penicillin

Penicillium mould

What clinical testing uses

Volunteers & patients

What is a placebo

Looks like drug but has no active ingredient & no effect

Single-blind trial definition

Only doctor knows who receives the drug

Double-blind trial definition

Neither patient nor doctor knows who gets drug

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