The Genetic Basis of Schizophrenia (OCR A-Level Psychology): Flashcards
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14 cards from this deck
Schizophrenia genetic explanation features
Schizophrenia genetic explanation features
Inherited and polygenic
MZ vs DZ concordance meaning
MZ vs DZ concordance meaning
Higher MZ rate suggests genetic link
Dopamine neurotransmitter type
Dopamine neurotransmitter type
Excitatory (makes neurons fire)
Dopamine hypothesis mechanism
Dopamine hypothesis mechanism
Too much dopamine or oversensitive D2 receptors
L-dopa
L-dopa
Synthetic dopamine-releasing drug (treats Parkinson's)
Antipsychotic drugs' mechanism
Antipsychotic drugs' mechanism
Inhibit dopamine activity
Hyperdopaminergia
Hyperdopaminergia
Excessive dopamine in subcortex/Broca's area
Hyperdopaminergia symptom link
Hyperdopaminergia symptom link
Positive symptoms
Hypodopaminergia
Hypodopaminergia
Low dopamine in prefrontal cortex
Hypodopaminergia symptom link
Hypodopaminergia symptom link
Negative symptoms
Concordance rate limitation
Concordance rate limitation
Not 100% - genes don't fully explain schizophrenia
MZ twin environmental limitation
MZ twin environmental limitation
MZ twins treated more similarly - suggests environmental factors
Family study finding
Family study finding
Closer relatives = higher schizophrenia risk
Adoption study purpose
Adoption study purpose
See if adopted children similar to biological parents