Immunotherapy (VCE SSCE Biology): Flashcards
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Practise the cards
10 cards from this deck
Immunotherapy
Immunotherapy
Modulates immune system functioning to treat disease
Two immunotherapy categories
Two immunotherapy categories
Activation (boost) and suppression (reduce)
Monoclonal antibodies (mAbs)
Monoclonal antibodies (mAbs)
Identical lab-made antibodies from plasma cell clones
Hybridoma
Hybridoma
Fusion of B lymphocyte and myeloma cell
ADCC mechanism
ADCC mechanism
mAbs mark cancer cells; NK cells destroy them
Conjugated mAbs
Conjugated mAbs
mAbs with toxic molecules attached (drugs/isotopes)
Apoptosis
Apoptosis
Programmed cell death
Autoimmune disease
Autoimmune disease
Immune system attacks own cells
Immunosuppression
Immunosuppression
Reduced immune system ability to respond
CAR-T therapy
CAR-T therapy
T cells modified with chimeric antigen receptors
