DNA & Protein Synthesis (AQA A-Level Biology): Quizzes

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Experimental Work Investigating the Role of Nucleic Acids
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What key experimental material did Nirenberg use to decipher the genetic code?

Synthetic mRNA molecules

Why were cell extracts treated with DNase in Nirenberg's experiments?

To remove genomic DNA

Which radioactive isotope was used to label phenylalanine in the key experiment?

Carbon-14

Which synthetic mRNA produced the highest radioactivity with labelled phenylalanine?

Poly U

Which amino acid is coded for by the codon UUU?

Phenylalanine

How many possible triplet codons exist in total?

64

How many codons serve as stop codons to terminate translation?

3

What does it mean that the genetic code is degenerate?

Multiple codons code for one amino acid

Is the genetic code ambiguous?

No, each codon codes for one amino acid

How did Khorana extend Nirenberg's work on the genetic code?

Creating longer repeating sequences

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