Gene Mutation (AQA A-Level Biology): Quizzes

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Gene Mutation
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What is a mutation?

Change in DNA quantity or base sequence

Why are mutations in gamete cells significant?

They are heritable and passed to offspring

How does the degenerate genetic code protect against substitution mutations?

Most amino acids coded by multiple triplets

Why are deletion mutations generally more severe than substitution mutations?

They affect entire protein downstream

What is a reading frame shift?

All subsequent triplets shifted by one

What is polyploidy?

Three or more complete chromosome sets

What is non-disjunction?

Homologous pairs fail to separate

How many chromosomes do individuals with Down's syndrome have?

47

How many chromosomes does bread wheat (Triticum aestivum) have?

42

How can substitution mutations affect enzyme function?

Active site may no longer fit substrate

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