Gene Mutations (AQA A-Level Biology): Quizzes

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Gene Mutations
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When do gene mutations typically occur?

During DNA replication

Which outcome is NOT possible for a substitution mutation?

Frame shift in reading frame

In sickle cell anaemia, which codon change occurs in the β-globin gene?

GAG to GTG

Why do deletion mutations cause frame shifts?

Genetic code read in triplets

What happens if three extra bases are added to a DNA sequence?

No frame shift occurs

What is a translocation mutation?

Bases move to different chromosome

What is the natural spontaneous mutation rate per generation?

1-2 per 100,000 genes

Which is an example of high energy ionising radiation that can cause mutations?

X-rays

Where must a mutation occur to be passed to offspring?

In gametes

What happens in an inversion mutation?

Bases rejoin in reverse order

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