Risk Factors & Cancer (AQA A-Level Biology): Quizzes

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Risk Factors & Cancer
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What is the most preventable cause of cancer according to modifiable lifestyle factors?

Smoking

Why does cancer risk increase with age?

Mutations accumulate over time

How many times greater is lung cancer risk for someone smoking 25 cigarettes daily vs non-smokers?

25 times

What happens when proto-oncogenes become mutated or overactivated?

They become oncogenes

What did dogs exposed to unfiltered cigarette smoke develop in experimental studies?

Pulmonary disease and early lung cancer

How does benzopyrene cause cancer at the cellular level?

Binds to DNA and causes mutations

What type of studies show correlations between factors and cancer?

Epidemiological studies

How many alleles of tumour suppressor genes must be mutated to lose their protective function?

Both alleles

How does oestrogen trigger cancer development in breast tissue?

Promotes transcription of division genes

What does gene therapy for cancer involve introducing into cancer cells?

Functional tumour suppressor genes

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