Apoptosis (VCE SSCE Biology): Flashcards
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Apoptosis
Apoptosis
Controlled/programmed cell death
Cells dying per minute via apoptosis
Cells dying per minute via apoptosis
300 million
Mitochondrial pathway (apoptosis)
Mitochondrial pathway (apoptosis)
Intrinsic pathway triggered by internal damage
Death receptor pathway (apoptosis)
Death receptor pathway (apoptosis)
Extrinsic pathway triggered by external signals
Cytochrome c release triggers formation of
Cytochrome c release triggers formation of
Apoptosome
Key difference: necrosis vs apoptosis
Key difference: necrosis vs apoptosis
Necrosis causes inflammation; apoptosis doesn't
Apoptotic bodies
Apoptotic bodies
Vesicles from dying cells, engulfed by phagocytes
Cancer
Cancer
Uncontrolled cell replication with migration ability
Metastasis
Metastasis
Migration of tumour cells to distant body parts
Effect of increased apoptosis in brain
Effect of increased apoptosis in brain
Neurological disorders, movement/cognitive issues
