Apoptosis (VCE SSCE Biology): Flashcards

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Apoptosis
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Apoptosis

Controlled/programmed cell death

Cells dying per minute via apoptosis

300 million

Mitochondrial pathway (apoptosis)

Intrinsic pathway triggered by internal damage

Death receptor pathway (apoptosis)

Extrinsic pathway triggered by external signals

Cytochrome c release triggers formation of

Apoptosome

Key difference: necrosis vs apoptosis

Necrosis causes inflammation; apoptosis doesn't

Apoptotic bodies

Vesicles from dying cells, engulfed by phagocytes

Cancer

Uncontrolled cell replication with migration ability

Metastasis

Migration of tumour cells to distant body parts

Effect of increased apoptosis in brain

Neurological disorders, movement/cognitive issues

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