Epigenetic Control of Gene Expression (AQA A-Level Biology): Quizzes

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Epigenetic Control of Gene Expression
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How do epigenetic changes differ from genetic mutations?

Epigenetic changes are reversible

What role does the epigenome play in cells?

Acts as cellular memory

What characterises loosely packed chromatin (euchromatin)?

DNA accessible, genes switched on

What happens when acetyl groups are removed from histones?

Histones become more positively charged

How does DNA methylation inhibit transcription?

Blocks factors & promotes deacetylation

Which combination silences gene expression?

Decreased acetylation, increased methylation

How is maternal care behaviour inherited in rats?

Through methylation patterns in epigenome

How does hypermethylation contribute to early cancer development?

Silences genes that prevent cancer

What do demethylating drugs achieve in epigenetic therapy?

Remove methyl groups, reactivate silenced genes

How does RNA interference (RNAi) control gene expression?

siRNA breaks down specific mRNA molecules

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