Scott-Van Zeeland et al. (2013) Role of EPHX2 Gene Variants in Anorexia Nervosa (Edexcel A-Level Psychology): Quizzes

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Scott-Van Zeeland et al. (2013) Role of EPHX2 Gene Variants in Anorexia Nervosa
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How many candidate genes were investigated in this anorexia nervosa study?

152 candidate genes

Which two genes were identified in the initial sequencing phase for further investigation?

ITPR3 and EPHX2

What biological process does the EPHX2 gene play a role in?

Cholesterol metabolism

How many patients with anorexia were in the initial sample?

261 patients

Which brain region showed high levels of EPHX2 gene expression?

Paraventricular nucleus of thalamus

What characteristic did anorexia patients with EPHX2 variants show regarding BMI?

Lowest BMI scores

Which assessment was used to measure depression levels in the study?

Beck's Depression Inventory

What is a key weakness regarding the initial sample composition?

All participants were female

Which methodological strength enhanced the reliability of genetic data collection?

Highly standardised methods & equipment

What depression-related finding was associated with EPHX2 variants in anorexia patients?

Highest depression scores

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