Hormonal Communication (OCR A-Level Biology A): Flashcards

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Control of Blood Glucose Concentration and Diabetes
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Normal blood glucose range in healthy individuals

4-8 mmol dm⁻³

Glycogenolysis

Breakdown of glycogen to release glucose

Gluconeogenesis

Synthesis of glucose from non-carbohydrate molecules

Glycogenesis

Conversion of glucose to glycogen for storage

Insulin's effect on blood glucose

Lowers blood glucose concentration

Glucagon's effect on blood glucose

Raises blood glucose concentration

Location of beta cells in pancreas

Islets of Langerhans

What triggers insulin release in beta cells

High ATP closes K⁺ channels, Ca²⁺ influx triggers release

Cause of Type 1 diabetes

Autoimmune destruction of pancreatic beta cells

Percentage of diabetes cases that are Type 2

90%

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