Genetics and Epigenetics (Leaving Cert Biology): Flashcards

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Genetics and Epigenetics
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Genetics

Study of heredity & how traits pass from parents to offspring

Epigenetics

Study of how behaviour/environment affect how genes work

Key difference: genetics vs epigenetics

Genetics = permanent DNA changes; epigenetics = reversible

Genome

Complete set of all genetic material in an organism

Gene

Specific section of DNA with instructions for making a protein

Methylation in epigenetics

CH3CH_3 group attaches to DNA & prevents gene from working

Histone modification

DNA wrapped too tightly around histones, turning gene off

Reversibility of epigenetic changes

Epigenetic changes are reversible, unlike genetic changes

Species definition

Similar organisms that can interbreed to produce fertile offspring

Chromosomes in human body cells

46 chromosomes

Chromosomes in human gametes (sperm/egg)

23 chromosomes

Dutch Hunger Winter (1944/45) showed

Epigenetic changes can pass to children & grandchildren

Himalayan rabbit fur pattern shows

White fur on warm body, darker fur on cool extremities

Smoking & epigenetics

Removes methyl groups, may cause cancer; reversible if stop

Nuclear DNA inheritance

Inherited equally from both parents (half from each)

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